MAP-kinase scaffold activity [GO_0005078]
The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0005078",
"symbol": "",
"types": [
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],
"short_form": "GO_0005078",
"label": "MAP-kinase scaffold activity"
},
"description": [
"The binding activity of a molecule that functions as a physical support for the assembly of a multiprotein mitogen-activated protein kinase (MAPK) complex. Binds multiple kinases of the MAPKKK cascade, and also upstream signaling proteins, permitting those molecules to function in a coordinated way. Bringing together multiple enzymes and their substrates enables the signal to be transduced quickly and efficiently."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0035591",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0035591",
"label": "signaling adaptor activity"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
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"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0043410",
"types": [
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"Class"
],
"short_form": "GO_0043410",
"label": "positive regulation of MAPK cascade"
}
},
{
"relation": {
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"label": "has part",
"type": "has_part"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0051019",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0051019",
"label": "mitogen-activated protein kinase binding"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "MAP-kinase scaffold protein activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": [
{
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
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