actin filament [GO_0005884]

A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.

Open actin filament in VFB

VFB Term Json

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            "short_form": "GO_0005884",
            "label": "actin filament"
        },
        "description": [
            "A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
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            "short_form": "GO_0099513",
            "label": "polymeric cytoskeletal fiber"
        }
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    "relationships": [
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                "short_form": "GO_0015629",
                "label": "actin cytoskeleton"
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    "anatomy_channel_image": [],
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