actin filament [GO_0005884]
A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane.
Note
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{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0005884",
"symbol": "",
"types": [
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],
"short_form": "GO_0005884",
"label": "actin filament"
},
"description": [
"A filamentous structure formed of a two-stranded helical polymer of the protein actin and associated proteins. Actin filaments are a major component of the contractile apparatus of skeletal muscle and the microfilaments of the cytoskeleton of eukaryotic cells. The filaments, comprising polymerized globular actin molecules, appear as flexible structures with a diameter of 5-9 nm. They are organized into a variety of linear bundles, two-dimensional networks, and three dimensional gels. In the cytoskeleton they are most highly concentrated in the cortex of the cell just beneath the plasma membrane."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0099513",
"types": [
"Entity",
"Anatomy",
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],
"short_form": "GO_0099513",
"label": "polymeric cytoskeletal fiber"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0015629",
"types": [
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"Class"
],
"short_form": "GO_0015629",
"label": "actin cytoskeleton"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "microfilament",
"type": ""
},
"pub": {
"core": {
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"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": [
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"label": ""
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"FlyBase": "",
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"DOI": ""
}
]
}
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