Defective GSS does not synthesize GSH [GO_0004363]
Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen Defective GSS does not synthesize GSH in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004363",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004363",
"label": "Defective GSS does not synthesize GSH"
},
"description": [
"Catalysis of the reaction: L-gamma-glutamyl-L-cysteine + ATP + glycine = ADP + glutathione + 2 H+ + phosphate."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_1904091",
"types": [
"Entity",
"Class"
],
"short_form": "GO_1904091",
"label": "non-ribosomal peptide synthetase activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016881",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016881",
"label": "acid-amino acid ligase activity"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0006750",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0006750",
"label": "glutathione biosynthetic process"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "GSH synthetase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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