negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [GO_0031586]
Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerVFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0031586",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0031586",
"label": "negative regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity"
},
"description": [
"Any process that stops, prevents, or reduces the frequency, rate or extent of the activity of the inositol 1,4,5-trisphosphate-sensitive calcium-release channel."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0050849",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0050849",
"label": "negative regulation of calcium-mediated signaling"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_2001258",
"types": [
"Entity",
"Class"
],
"short_form": "GO_2001258",
"label": "negative regulation of cation channel activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_1901020",
"types": [
"Entity",
"Class"
],
"short_form": "GO_1901020",
"label": "negative regulation of calcium ion transmembrane transporter activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0051280",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0051280",
"label": "negative regulation of release of sequestered calcium ion into cytosol"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0031585",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0031585",
"label": "regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002212",
"label": "negatively regulates",
"type": "negatively_regulates"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0005220",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0005220",
"label": "inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "down-regulation of IP3 receptor activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "down regulation of IP3 receptor activity",
"type": ""
},
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "downregulation of IP3 receptor activity",
"type": ""
},
"pub": {
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"label": ""
},
"FlyBase": "",
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}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "inhibition of IP3 receptor activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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