ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) [GO_0004181]

Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
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Open ACE2 hydrolyzes Angiotensin-(1-8) to Angiotensin-(1-7) in VFB

VFB Term Json

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            "Catalysis of the hydrolysis of a single C-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."
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            "label": "CNDP2:2Mn2+ dimer hydrolyses CysGly"
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