DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity [GO_0008657]

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            "short_form": "GO_0008657",
            "label": "DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) inhibitor activity"
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        "description": [
            "Binds to and stops, prevents or reduces the activity of ATP-hydrolyzing DNA topoisomerase. ATP-hydrolyzing DNA topoisomerase catalyzes the DNA topological transformation by transiently cleaving a pair of complementary DNA strands to form a gate through which a second double-stranded DNA segment is passed, after which the severed strands in the first DNA segment are rejoined; product release is coupled to ATP binding and hydrolysis; changes the linking number in multiples of 2."
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            "short_form": "GO_0004857",
            "label": "enzyme inhibitor activity"
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            "short_form": "GO_0072586",
            "label": "DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) regulator activity"
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                "label": "DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"
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