iodotyrosine deiodinase activity [GO_0140616]

Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.
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Open iodotyrosine deiodinase activity in VFB

Term Information

  • ID: GO_0140616
  • Name: iodotyrosine deiodinase activity
  • Definition: Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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        },
        "description": [
            "Catalyzes the reaction: 2 iodide + L-tyrosine + 2 NADP+ = 3,5-diiodo-L-tyrosine + H+ + 2 NADPH. Note that this activity has only been demonstrated in the direction of 3-deiodination. 3-bromo-L-tyrosine and 3-chloro-L-tyrosine can also be used as substrates."
        ],
        "comment": []
    },
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            "label": "oxidoreductase activity, acting on X-H and Y-H to form an X-Y bond"
        }
    ],
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    "anatomy_channel_image": [],
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