Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines [GO_0004656]
Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004656",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004656",
"label": "Prolyl 4-hydroxylase converts collagen prolines to 4-hydroxyprolines"
},
"description": [
"Catalysis of the reaction: procollagen L-proline + 2-oxoglutarate + O2 = procollagen trans-4-hydroxy-L-proline + succinate + CO2."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0019798",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0019798",
"label": "procollagen-proline dioxygenase activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0031545",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0031545",
"label": "Cytosolic PHD2,3 hydroxylates proline residues on HIF1A"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "procollagen-proline,2-oxoglutarate-4-dioxygenase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_related_synonym",
"label": "protocollagen proline 4-hydroxylase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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