SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters [GO_0046969]

Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
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Open SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters in VFB

Term Information

  • ID: GO_0046969
  • Name: SIRT6 deacetylates histones at NOTCH1 and NOTCH4 gene promoters
  • Definition: Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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            "Catalysis of the reaction: histone H3 N6-acetyl-L-lysine (position 9) + H2O = histone H3 L-lysine (position 9) + acetate. This reaction requires the presence of NAD, and represents the removal of an acetyl group from lysine at position 9 of the histone H3 protein."
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            "short_form": "GO_0032129",
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            "label": "histone H3K9 deacetylase activity"
        }
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