transforming growth factor beta receptor activity [GO_0005024]
Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate. Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under ’transmembrane signaling receptor activity ; GO:0004888.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen transforming growth factor beta receptor activity in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0005024",
"symbol": "",
"types": [
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],
"short_form": "GO_0005024",
"label": "transforming growth factor beta receptor activity"
},
"description": [
"Combining with a transforming growth factor beta (TGFbeta) and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity by catalysis of the reaction: ATP protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate."
],
"comment": [
"Note that this term represents an activity and not a gene product, and should only be used when the receptor binds the ligand TGFbeta. For binding to other growth factors, consider annotating to terms under 'transmembrane signaling receptor activity ; GO:0004888."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0004675",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004675",
"label": "Activated type I receptor phosphorylates R-Smad1/5/8 directly"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
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"label": "TGFbeta receptor activity",
"type": ""
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},
{
"synonym": {
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{
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}
},
{
"synonym": {
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"label": "TGFbetaR",
"type": ""
},
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}
}
],
"def_pubs": [
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"label": ""
},
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"DOI": ""
}
]
}
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