Tryptophan is hydroxylated [GO_0004510]

Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
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Open Tryptophan is hydroxylated in VFB

Term Information

  • ID: GO_0004510
  • Name: Tryptophan is hydroxylated
  • Definition: Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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            "label": "Tryptophan is hydroxylated"
        },
        "description": [
            "Catalysis of the reaction: L-tryptophan + tetrahydrobiopterin + O2 = 5-hydroxy-L-tryptophan + 4-alpha-hydroxytetrahydrobiopterin + H2O."
        ],
        "comment": []
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            "short_form": "GO_0016714",
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            "label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen"
        }
    ],
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                "label": "L-tryptophan hydroxylase activity",
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