yolk sac [UBERON_0001040]
A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman’s]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP].
Note
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{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/UBERON_0001040",
"symbol": "",
"types": [
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"short_form": "UBERON_0001040",
"label": "yolk sac"
},
"description": [
"A sac-like expansion of the ventral wall of the intestine, narrowed into a yolk stalk near the body[Hyman's]. Membranous sac attached to an embryo, providing early nourishment in the form of yolk in bony fishes, sharks, reptiles, birds, and primitive mammals. It functions as the developmental circulatory system of the human embryo, before internal circulation begins. In the mouse, the yolk sac is the first site of blood formation, generating primitive macrophages and erythrocytes[WP]."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0007499",
"types": [
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"short_form": "UBERON_0007499",
"label": "epithelial sac"
},
{
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"iri": "http://purl.obolibrary.org/obo/UBERON_0005292",
"types": [
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"short_form": "UBERON_0005292",
"label": "extraembryonic tissue"
},
{
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"iri": "http://purl.obolibrary.org/obo/UBERON_0005631",
"types": [
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"short_form": "UBERON_0005631",
"label": "extraembryonic membrane"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002254",
"label": "has developmental contribution from",
"type": "has_developmental_contribution_from"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/UBERON_0000925",
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"short_form": "UBERON_0000925",
"label": "endoderm"
}
},
{
"relation": {
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"label": "has developmental contribution from",
"type": "has_developmental_contribution_from"
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"iri": "http://purl.obolibrary.org/obo/UBERON_0004872",
"types": [
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"short_form": "UBERON_0004872",
"label": "splanchnic layer of lateral plate mesoderm"
}
}
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"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "saccus vitellinus",
"type": "http://purl.obolibrary.org/obo/uberon/core#LATIN"
},
"pub": {
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"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
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"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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