3'-tyrosyl-DNA phosphodiesterase activity [GO_0017005]

Catalysis of the hydrolysis of 3’-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA. See also the molecular function term ‘DNA topoisomerase type I activity ; GO:0003917’.
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Open 3’-tyrosyl-DNA phosphodiesterase activity in VFB

Term Information

  • ID: GO_0017005
  • Name: 3’-tyrosyl-DNA phosphodiesterase activity
  • Definition: Catalysis of the hydrolysis of 3’-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA.
  • Synonyms:
  • Type:
  • Comment: See also the molecular function term ‘DNA topoisomerase type I activity ; GO:0003917’.

VFB Term Json

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            "label": "3'-tyrosyl-DNA phosphodiesterase activity"
        },
        "description": [
            "Catalysis of the hydrolysis of 3'-phosphotyrosyl groups formed as covalent intermediates (in DNA backbone breakage) between DNA topoisomerase I and DNA."
        ],
        "comment": [
            "See also the molecular function term 'DNA topoisomerase type I activity ; GO:0003917'."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
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            "iri": "http://purl.obolibrary.org/obo/GO_0070259",
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            "short_form": "GO_0070259",
            "unique_facets": [
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            "label": "tyrosyl-DNA phosphodiesterase activity"
        }
    ],
    "relationships": [],
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    "anatomy_channel_image": [],
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