Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter [GO_0042800]
Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group to the lysine residue at position 4 of the histone H3 protein. Note that in some species, the methyl group may be added to a lysine in a slightly different position of the histone H3 protein, but that this term still applies.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter in VFB
VFB Term Json
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"Catalysis of the reaction: S-adenosyl-L-methionine + histone H3 L-lysine (position 4) = S-adenosyl-L-homocysteine + histone H3 N6-methyl-L-lysine (position 4). This reaction is the addition of a methyl group to the lysine residue at position 4 of the histone H3 protein."
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"comment": [
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