cysteine-type endopeptidase activity involved in apoptotic signaling pathway [GO_0097199]

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway. Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.
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Open cysteine-type endopeptidase activity involved in apoptotic signaling pathway in VFB

Term Information

  • ID: GO_0097199
  • Name: cysteine-type endopeptidase activity involved in apoptotic signaling pathway
  • Definition: Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway.
  • Synonyms:
  • Type:
  • Comment: Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases.

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0097199",
            "symbol": "",
            "types": [
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            "short_form": "GO_0097199",
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            "label": "cysteine-type endopeptidase activity involved in apoptotic signaling pathway"
        },
        "description": [
            "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which the sulfhydryl group of a cysteine residue at the active center acts as a nucleophile, and contributing to the apoptotic signaling pathway."
        ],
        "comment": [
            "Examples of gene products that may be annotated to this term include CASP2, CASP8, CASP9, and CASP10, also called initiator (or apical, or activator) caspases."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
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        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0097153",
            "types": [
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                "has_subClass"
            ],
            "short_form": "GO_0097153",
            "unique_facets": [
                "Class"
            ],
            "label": "The PIDDosome activates CASP2"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0097190",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0097190",
                "unique_facets": [
                    "Class"
                ],
                "label": "apoptotic signaling pathway"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "apical caspase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
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                    "short_form": "Unattributed",
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                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
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                "type": ""
            },
            "pub": {
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        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "initiator caspase activity",
                "type": ""
            },
            "pub": {
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    "def_pubs": []
}