Defective PAH does not hydroxylate L-Phe to L-Tyr [GO_0004505]
Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen Defective PAH does not hydroxylate L-Phe to L-Tyr in VFB
Term Information
- ID: GO_0004505
- Name: Defective PAH does not hydroxylate L-Phe to L-Tyr
- Definition: Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin.
- Synonyms:
- Type:
- Comment:
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004505",
"symbol": "",
"types": [
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"Class"
],
"short_form": "GO_0004505",
"unique_facets": [
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],
"label": "Defective PAH does not hydroxylate L-Phe to L-Tyr"
},
"description": [
"Catalysis of the reaction: L-phenylalanine + tetrahydrobiopterin + O2 = L-tyrosine + 4-alpha-hydroxytetrahydrobiopterin."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "275438e",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016714",
"types": [
"Entity",
"Class",
"has_subClass"
],
"short_form": "GO_0016714",
"unique_facets": [
"Class"
],
"label": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0019293",
"types": [
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],
"short_form": "GO_0019293",
"unique_facets": [
"Class"
],
"label": "tyrosine biosynthetic process, by oxidation of phenylalanine"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "phenylalanine hydroxylase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"short_form": "Unattributed",
"unique_facets": [
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],
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_related_synonym",
"label": "PAH activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"label": ""
},
"FlyBase": "",
"PubMed": "",
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}
}
],
"def_pubs": []
}
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