DNA (cytosine-5-)-methyltransferase activity [GO_0003886]

Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine. Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37).

Open DNA (cytosine-5-)-methyltransferase activity in VFB

Term Information

  • ID: GO_0003886
  • Name: DNA (cytosine-5-)-methyltransferase activity
  • Definition: Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine.
  • Synonyms:
  • Type:
  • Comment: Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37).

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0003886",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0003886",
            "unique_facets": [
                "Class"
            ],
            "label": "DNA (cytosine-5-)-methyltransferase activity"
        },
        "description": [
            "Catalysis of the reaction: S-adenosyl-L-methionine + DNA containing cytosine = S-adenosyl-L-homocysteine + DNA containing 5-methylcytosine."
        ],
        "comment": [
            "Note that EC:2.1.1.73 was deleted from EC as the reaction is performed by DNA (cytosine-5-)-methyltransferase (EC:2.1.1.37)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0009008",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0009008",
            "unique_facets": [
                "Class"
            ],
            "label": "DNA-methyltransferase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008757",
            "types": [
                "Entity",
                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0008757",
            "unique_facets": [
                "Class"
            ],
            "label": "S-adenosylmethionine-dependent methyltransferase activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0090116",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0090116",
                "unique_facets": [
                    "Class"
                ],
                "label": "C-5 methylation of cytosine"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "site-specific DNA-methyltransferase (cytosine-specific) activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}