DNA-templated transcription initiation [GO_0006352]

The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place. Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.
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Open DNA-templated transcription initiation in VFB

Term Information

  • ID: GO_0006352
  • Name: DNA-templated transcription initiation
  • Definition: The initial step of transcription, consisting of the assembly of the RNA polymerase preinitiation complex (PIC) at a gene promoter, as well as the formation of the first few bonds of the RNA transcript. Transcription initiation includes abortive initiation events, which occur when the first few nucleotides are repeatedly synthesized and then released, and ends when promoter clearance takes place.
  • Synonyms:
  • Type:
  • Comment: Note that promoter clearance is represented as a separate step, not part_of either initiation or elongation.

VFB Term Json

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