histone H3K27 dimethyltransferase activity [GO_0140952]

Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.
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Open histone H3K27 dimethyltransferase activity in VFB

Term Information

  • ID: GO_0140952
  • Name: histone H3K27 dimethyltransferase activity
  • Definition: Catalysis of the reaction: L-lysyl27-[histone H3] + 2 S-adenosyl-L-methionine = 2 H+ + N6,N6-dimethyl-L-lysyl27-[histone H3] + 2 S-adenosyl-L-homocysteine. This reaction is the successive addition of two methyl groups to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me2.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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