histone H3K27 monomethyltransferase activity [GO_0140953]

Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me.

Open histone H3K27 monomethyltransferase activity in VFB

Term Information

  • ID: GO_0140953
  • Name: histone H3K27 monomethyltransferase activity
  • Definition: Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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            "Catalysis of the reaction: L-lysyl27-[histone H3] + S-adenosyl-L-methionine = H+ + N6-methyl-L-lysyl27-[histone H3] + S-adenosyl-L-homocysteine. This reaction is the addition of a single methyl group to the unmethylated lysine residue at position 27 of histone H3, producing histone H3K27me."
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            "label": "PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter"
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