HMGCR dimer reduces bHMG-CoA to MVA [GO_0004420]

Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH.
Tags:

Open HMGCR dimer reduces bHMG-CoA to MVA in VFB

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004420",
            "symbol": "",
            "types": [
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            ],
            "short_form": "GO_0004420",
            "label": "HMGCR dimer reduces bHMG-CoA to MVA"
        },
        "description": [
            "Catalysis of the reaction: (R)-mevalonate + CoA + 2 NADP+ = (S)-3-hydroxy-3-methylglutaryl-CoA + 2 H+ + 2 NADPH."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016616",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016616",
            "label": "RDH11 reduces RBP2:atRAL to RBP2:atROL"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_related_synonym",
                "label": "hydroxymethylglutaryl-CoA reductase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}