hydroxymethylbilane synthase activity [GO_0004418]

Catalysis of the reaction: H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4. Note that this function was formerly EC:4.3.1.8.

Open hydroxymethylbilane synthase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004418",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004418",
            "label": "hydroxymethylbilane synthase activity"
        },
        "description": [
            "Catalysis of the reaction: H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4."
        ],
        "comment": [
            "Note that this function was formerly EC:4.3.1.8."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016765",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0016765",
            "label": "DHDDS:NUS1 elongates E,E-FPP with (n)IPPP to form pPPP"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "uroporphyrinogen I synthetase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}