IkappaB kinase activity [GO_0008384]
Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein. Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen IkappaB kinase activity in VFB
Term Information
- ID: GO_0008384
- Name: IkappaB kinase activity
- Definition: Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein.
- Synonyms:
- Type:
- Comment: Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB.
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0008384",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0008384",
"unique_facets": [
"Class"
],
"label": "IkappaB kinase activity"
},
"description": [
"Catalysis of the reaction: ATP + IkappaB protein = ADP + IkappaB phosphoprotein."
],
"comment": [
"Note that phosphorylation of IkappaB targets it for proteasomal degradation and allows the nuclear translocation of kB."
]
},
"query": "Get JSON for Class",
"version": "275438e",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0004674",
"types": [
"Entity",
"Class",
"has_subClass"
],
"short_form": "GO_0004674",
"unique_facets": [
"Class"
],
"label": "Activation of NLK"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0007252",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0007252",
"unique_facets": [
"Class"
],
"label": "I-kappaB phosphorylation"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "TANK-binding kinase 1 activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"unique_facets": [
"pub"
],
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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