iron ion transmembrane transporter inhibitor activity [GO_0097690]

Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter. An example of this is human hepcidin (UniProt symbol P81172), which regulates iron transport out of cells (see PMID:15514116).

Open iron ion transmembrane transporter inhibitor activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0097690",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0097690",
            "label": "iron ion transmembrane transporter inhibitor activity"
        },
        "description": [
            "Binds to and stops, prevents, or reduces the activity of an iron ion transmembrane transporter."
        ],
        "comment": [
            "An example of this is human hepcidin (UniProt symbol P81172), which regulates iron transport out of cells (see PMID:15514116)."
        ]
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0140678",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0140678",
            "label": "molecular function inhibitor activity"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002212",
                "label": "negatively regulates",
                "type": "negatively_regulates"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0005381",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0005381",
                "label": "Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "iron channel inhibitor activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
                    "Entity",
                    "Individual",
                    "pub"
                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}