metalloaminopeptidase activity [GO_0070006]

Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Open metalloaminopeptidase activity in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0070006",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0070006",
            "label": "metalloaminopeptidase activity"
        },
        "description": [
            "Catalysis of the hydrolysis of a single N-terminal amino acid residue from a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004177",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004177",
            "label": "Trimming of N-ter extended precursor fragments by cytosolic aminopeptidases"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008235",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008235",
            "label": "metalloexopeptidase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}