miRNA-mediated gene silencing by mRNA destabilization [GO_0035279]

An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism.
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Open miRNA-mediated gene silencing by mRNA destabilization in VFB

VFB Term Json

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            "An RNA interference pathway in which microRNAs (miRNAs) direct the cleavage of target mRNAs. Once incorporated into a RNA-induced silencing complex (RISC), a miRNA base pairing with near-perfect complementarity to the target mRNA will typically direct targeted endonucleolytic cleavage of the mRNA. Many plant miRNAs downregulate gene expression through this mechanism."
        ],
        "comment": []
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    "query": "Get JSON for Class",
    "version": "44725ae",
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            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0035195",
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            "iri": "http://purl.obolibrary.org/obo/GO_0061157",
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            "short_form": "GO_0061157",
            "label": "mRNA destabilization"
        }
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