mRNA destabilization [GO_0061157]

Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns.

Open mRNA destabilization in VFB

VFB Term Json

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        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0061157",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061157",
            "label": "mRNA destabilization"
        },
        "description": [
            "Any process that decreases the stability of an mRNA molecule, making it more vulnerable to degradative processes. Messenger RNA is the intermediate molecule between DNA and protein. It includes UTR and coding sequences. It does not contain introns."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0017148",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0017148",
            "label": "negative regulation of translation"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0061014",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0061014",
            "label": "positive regulation of mRNA catabolic process"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0050779",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0050779",
            "label": "RNA destabilization"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0043488",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0043488",
            "label": "regulation of mRNA stability"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [],
    "def_pubs": [
        {
            "core": {
                "symbol": "",
                "iri": "http://flybase.org/reports/Unattributed",
                "types": [
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                ],
                "short_form": "Unattributed",
                "label": ""
            },
            "FlyBase": "",
            "PubMed": "",
            "DOI": ""
        }
    ]
}