MRSBs reduce L-methyl-(R)-S-oxide to L-methionine [GO_0033743]
Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen MRSBs reduce L-methyl-(R)-S-oxide to L-methionine in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0033743",
"symbol": "",
"types": [
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"Class"
],
"short_form": "GO_0033743",
"label": "MRSBs reduce L-methyl-(R)-S-oxide to L-methionine"
},
"description": [
"Catalysis of the reaction: peptide-L-methionine + H2O + thioredoxin disulfide = peptide-L-methionine (R)-S-oxide + thioredoxin. Can act on oxidized methionine in peptide linkage with specificity for the R enantiomer. Thioredoxin disulfide is the oxidized form of thioredoxin."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016671",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016671",
"label": "oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "protein-methionine-R-oxide reductase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "methionine sulfoxide reductase B activity",
"type": ""
},
"pub": {
"core": {
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"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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