MTA2-NuRD complex deacetylates TP53 [GO_0004407]
Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen MTA2-NuRD complex deacetylates TP53 in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004407",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004407",
"label": "MTA2-NuRD complex deacetylates TP53"
},
"description": [
"Catalysis of the reaction: histone N6-acetyl-L-lysine + H2O = histone L-lysine + acetate. This reaction represents the removal of an acetyl group from a histone, a class of proteins complexed to DNA in chromatin and chromosomes."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0033558",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0033558",
"label": "HDAC4 deacetylates RUNX3"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016811",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016811",
"label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/BFO_0000050",
"label": "is part of",
"type": "part_of"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016570",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016570",
"label": "histone modification"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [],
"def_pubs": [
{
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
]
}
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.