negative regulation of telomerase activity [GO_0051974]
Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen negative regulation of telomerase activity in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0051974",
"symbol": "",
"types": [
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],
"short_form": "GO_0051974",
"label": "negative regulation of telomerase activity"
},
"description": [
"Any process that stops or reduces the activity of the enzyme telomerase, which catalyzes of the reaction: deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_2000279",
"types": [
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],
"short_form": "GO_2000279",
"label": "negative regulation of DNA biosynthetic process"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0051972",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0051972",
"label": "regulation of telomerase activity"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0051348",
"types": [
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],
"short_form": "GO_0051348",
"label": "negative regulation of transferase activity"
}
],
"relationships": [
{
"relation": {
"iri": "http://purl.obolibrary.org/obo/RO_0002212",
"label": "negatively regulates",
"type": "negatively_regulates"
},
"object": {
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0003720",
"types": [
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],
"short_form": "GO_0003720",
"label": "Elongation Of The Telomeric Chromosome End"
}
}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "telomerase inhibitor",
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},
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},
{
"synonym": {
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"label": "downregulation of telomerase activity",
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},
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{
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},
{
"synonym": {
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"label": ""
},
"FlyBase": "",
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}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "inhibition of telomerase activity",
"type": ""
},
"pub": {
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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