NEIL3 cleaves 5-guanidinohydantoin [GO_0019104]
Catalysis of the removal of damaged bases by cleaving the N-C1’ glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0019104",
"symbol": "",
"types": [
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],
"short_form": "GO_0019104",
"label": "NEIL3 cleaves 5-guanidinohydantoin"
},
"description": [
"Catalysis of the removal of damaged bases by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apurinic/apyrimidinic (AP) site."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0140097",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0140097",
"label": "catalytic activity, acting on DNA"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016799",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016799",
"label": "hydrolase activity, hydrolyzing N-glycosyl compounds"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "DNA glycosylase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_related_synonym",
"label": "endonuclease VIII activity",
"type": ""
},
"pub": {
"core": {
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"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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