OMA1 hydrolyses OPA1 [GO_0004222]

Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

Open OMA1 hydrolyses OPA1 in VFB

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0004222",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004222",
            "label": "OMA1 hydrolyses OPA1"
        },
        "description": [
            "Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008237",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008237",
            "label": "Anthrax lef cleaves target cell MAP2K7 (MEK7)"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0004175",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0004175",
            "label": "CFTR F508del is degraded by the 26S proteasome"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "metalloendoproteinase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}