polypeptide N-acetylgalactosaminyltransferase activity [GO_0004653]
Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen polypeptide N-acetylgalactosaminyltransferase activity in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004653",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004653",
"label": "polypeptide N-acetylgalactosaminyltransferase activity"
},
"description": [
"Catalysis of the reaction: UDP-N-acetyl-D-galactosamine + polypeptide = UDP + N-acetyl-D-galactosaminyl-polypeptide. This reaction is the modification of serine or threonine residues in polypeptide chains by the transfer of a N-acetylgalactose from UDP-N-acetylgalactose to the hydroxyl group of the amino acid; it is the first step in O-glycan biosynthesis."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0008376",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0008376",
"label": "B4GALNT2 transfers GalNAc to Type 2 MSGG to form Sda"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0140096",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0140096",
"label": "catalytic activity, acting on a protein"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "UDP-GalNAc:polypeptide N-acetylgalactosaminyl transferase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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