post-translational protein modification [GO_0043687]

The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome. This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.
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Open post-translational protein modification in VFB

Term Information

  • ID: GO_0043687
  • Name: post-translational protein modification
  • Definition: The process of covalently altering one or more amino acids in a protein after the protein has been completely translated and released from the ribosome.
  • Synonyms:
  • Type:
  • Comment: This term should only be used to annotate a protein modification process that occurs after the protein has been released from the ribosome, and is therefore strictly post-translational. Modification of a free protein (one not attached to a ribosome) and modification of a C-terminal residue are post-translational processes. Some protein modifications occur while the protein is still in the ribosome but before translation has been completed; these modification processes are considered co-translational and should not be annotated using this term.

VFB Term Json

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