PP2A methylation by LCMT1 [GO_0018423]

Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.
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Open PP2A methylation by LCMT1 in VFB

Term Information

  • ID: GO_0018423
  • Name: PP2A methylation by LCMT1
  • Definition: Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0018423",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0018423",
            "unique_facets": [
                "Class"
            ],
            "label": "PP2A methylation by LCMT1"
        },
        "description": [
            "Catalysis of the reaction: S-adenosyl-L-methionine + protein L-leucine = S-adenosyl-L-homocysteine + protein L-leucine methyl ester. This modification occurs only at the oxygen atoms of the free alpha carboxyl group of a leucine residue at the C-terminus of the protein."
        ],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "3b19da3",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0003880",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0003880",
            "unique_facets": [
                "Class"
            ],
            "label": "protein C-terminal carboxyl O-methyltransferase activity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0008757",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0008757",
            "unique_facets": [
                "Class"
            ],
            "label": "S-adenosylmethionine-dependent methyltransferase activity"
        }
    ],
    "relationships": [],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "protein-leucine O-methyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "unique_facets": [
                        "pub"
                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_narrow_synonym",
                "label": "protein phosphatase methyltransferase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    ],
                    "short_form": "Unattributed",
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                    ],
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}