protein-succinyllysine desuccinylase activity [GO_0036055]

Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD+ = 2’’-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide. This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.

Open protein-succinyllysine desuccinylase activity in VFB

Term Information

  • ID: GO_0036055
  • Name: protein-succinyllysine desuccinylase activity
  • Definition: Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD+ = 2’’-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide.
  • Synonyms:
  • Type:
  • Comment: This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide.

VFB Term Json

{
    "term": {
        "core": {
            "iri": "http://purl.obolibrary.org/obo/GO_0036055",
            "symbol": "",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "GO_0036055",
            "unique_facets": [
                "Class"
            ],
            "label": "protein-succinyllysine desuccinylase activity"
        },
        "description": [
            "Catalysis of the reaction: H2O + N(6)-succinyl-L-lysyl-[protein] + NAD+ = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide."
        ],
        "comment": [
            "This reaction is the removal of a succinyl group (CO-CH2-CH2-CO) from a succinylated lysine residue of a protein or peptide."
        ]
    },
    "query": "Get JSON for Class",
    "version": "275438e",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/GO_0016811",
            "types": [
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                "Class",
                "has_subClass"
            ],
            "short_form": "GO_0016811",
            "unique_facets": [
                "Class"
            ],
            "label": "hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/BFO_0000050",
                "label": "is part of",
                "type": "part_of"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0036049",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0036049",
                "unique_facets": [
                    "Class"
                ],
                "label": "peptidyl-lysine desuccinylation"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_broad_synonym",
                "label": "succinyllysine desuccinylase activity",
                "type": ""
            },
            "pub": {
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                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "peptidyl-succinyllysine desuccinylase activity",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                    "label": ""
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                "DOI": ""
            }
        }
    ],
    "def_pubs": [
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                "label": ""
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            "FlyBase": "",
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    ]
}