pyrimidine-specific mismatch base pair DNA N-glycosylase activity [GO_0008263]
Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1’ glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site.
Note
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VFB Term Json
{
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"short_form": "GO_0008263",
"label": "pyrimidine-specific mismatch base pair DNA N-glycosylase activity"
},
"description": [
"Catalysis of the removal of mismatched pyrimidine bases in DNA. Enzymes with this activity recognize and remove pyrimidines present in mismatches by cleaving the N-C1' glycosidic bond between the target damaged DNA base and the deoxyribose sugar. The reaction releases a free base and leaves an apyrimidinic (AP) site."
],
"comment": []
},
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"version": "44725ae",
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"iri": "http://purl.obolibrary.org/obo/GO_0000700",
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"short_form": "GO_0000700",
"label": "mismatch base pair DNA N-glycosylase activity"
}
],
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