RNase H-mediated cleavage of the template strand [GO_0004523]
Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5’-phosphomonoesters. Note that the EC recommended name for this enzyme activity is ‘calf thymus ribonuclease H’, even though it is found in many species.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen RNase H-mediated cleavage of the template strand in VFB
Term Information
- ID: GO_0004523
- Name: RNase H-mediated cleavage of the template strand
- Definition: Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5’-phosphomonoesters.
- Synonyms:
- Type:
- Comment: Note that the EC recommended name for this enzyme activity is ‘calf thymus ribonuclease H’, even though it is found in many species.
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004523",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004523",
"unique_facets": [
"Class"
],
"label": "RNase H-mediated cleavage of the template strand"
},
"description": [
"Catalysis of the endonucleolytic cleavage of RNA in RNA-DNA hybrids to 5'-phosphomonoesters."
],
"comment": [
"Note that the EC recommended name for this enzyme activity is 'calf thymus ribonuclease H', even though it is found in many species."
]
},
"query": "Get JSON for Class",
"version": "3b19da3",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0016891",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0016891",
"unique_facets": [
"Class"
],
"label": "RNA endonuclease activity, producing 5'-phosphomonoesters"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
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"label": "calf thymus ribonuclease H activity",
"type": ""
},
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"core": {
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"label": ""
},
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},
{
"synonym": {
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"label": "ribonuclease H3 activity",
"type": ""
},
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},
{
"synonym": {
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"label": "ribonuclease H1 activity",
"type": ""
},
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"label": ""
},
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}
},
{
"synonym": {
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"label": "RNase H2 activity",
"type": ""
},
"pub": {
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"label": ""
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}
},
{
"synonym": {
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},
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"label": ""
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},
{
"synonym": {
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"type": ""
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"label": ""
},
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}
},
{
"synonym": {
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"label": "RNase H1 activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"unique_facets": [
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],
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "RNase H3 activity",
"type": ""
},
"pub": {
"core": {
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"iri": "http://flybase.org/reports/Unattributed",
"types": [
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],
"short_form": "Unattributed",
"unique_facets": [
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],
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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