sigma factor activity [GO_0016987]

Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
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Open sigma factor activity in VFB

Term Information

  • ID: GO_0016987
  • Name: sigma factor activity
  • Definition: Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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            "short_form": "GO_0016987",
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            "label": "sigma factor activity"
        },
        "description": [
            "Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins."
        ],
        "comment": []
    },
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            "label": "DNA-binding transcription factor activity"
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        },
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        },
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