SOCS family protein binding [GO_0097678]
Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions.
Note
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VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0097678",
"symbol": "",
"types": [
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"short_form": "GO_0097678",
"label": "SOCS family protein binding"
},
"description": [
"Binding to a member of the suppressor of cytokine signaling (SOCS) family of proteins. SOCS represent an important mechanism to extinguish cytokine and growth factor receptor signaling. Individual SOCS proteins are typically induced by specific cytokines and growth factors, thereby generating a negative feedback loop. SOCS proteins have important functions in development and homeostasis, and in disease, particularly tumor suppression and anti-inflammatory functions."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0005515",
"types": [
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"Class"
],
"short_form": "GO_0005515",
"label": "protein binding"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "suppressor of cytokine signaling family protein binding",
"type": ""
},
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"iri": "http://flybase.org/reports/Unattributed",
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"short_form": "Unattributed",
"label": ""
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"FlyBase": "",
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}
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