transcription cis-regulatory region binding [GO_0000976]
Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon. Note that this term is meant to also capture non-specific binding to regulatory regions. Also, to minimize ambiguity in the use of the word “promoter” in GO, we have chosen the phrase “transcription regulatory region” to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the “core promoter” where the basal transcription machinery binds, the “core promoter proximal region” where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen transcription cis-regulatory region binding in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0000976",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0000976",
"label": "transcription cis-regulatory region binding"
},
"description": [
"Binding to a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon."
],
"comment": [
"Note that this term is meant to also capture non-specific binding to regulatory regions. Also, to minimize ambiguity in the use of the word \"promoter\" in GO, we have chosen the phrase \"transcription regulatory region\" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the \"core promoter\" where the basal transcription machinery binds, the \"core promoter proximal region\" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_1990837",
"types": [
"Entity",
"Class"
],
"short_form": "GO_1990837",
"label": "sequence-specific double-stranded DNA binding"
},
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0001067",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0001067",
"label": "transcription regulatory region nucleic acid binding"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_broad_synonym",
"label": "regulatory region DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_exact_synonym",
"label": "transcription regulatory region sequence-specific DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "bacterial-type RNA polymerase regulatory region DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "bacterial-type RNA polymerase transcription regulatory region sequence-specific DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_related_synonym",
"label": "transcription regulatory region DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "eubacterial-type RNA polymerase regulatory region DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "eubacterial-type RNA polymerase regulatory region sequence-specific DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
Feedback
Was this page helpful?
Glad to hear it! Please tell us how we can improve.
Sorry to hear that. Please tell us how we can improve.