RNA polymerase I preinitiation complex assembly [GO_0001188]

The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.
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Open RNA polymerase I preinitiation complex assembly in VFB

Term Information

  • ID: GO_0001188
  • Name: RNA polymerase I preinitiation complex assembly
  • Definition: The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides.
  • Synonyms:
  • Type:
  • Comment:

VFB Term Json

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        "description": [
            "The formation of a large multiprotein-DNA complex that self-assembles on gene promoter through the sequential recruitment of the general initiation factors that compose the preinitiation complex (PIC) (which includes including UBF, SL1, RRN3 and TBP in human). The PIC engages RNA polymerase I on its DNA template strand and sparks polymerization of the first few RNA nucleotides."
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            "label": "transcription preinitiation complex assembly"
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                "short_form": "GO_0006361",
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                "label": "transcription initiation at RNA polymerase I promoter"
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