RNA polymerase II transcription regulatory region sequence-specific DNA binding [GO_0000977]
Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II. To minimize ambiguity in the use of the word “promoter” in GO, we have chosen the phrase “transcription regulatory region” to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the “core promoter” where the basal transcription machinery binds, the “core promoter proximal region” where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen RNA polymerase II transcription regulatory region sequence-specific DNA binding in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0000977",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0000977",
"label": "RNA polymerase II transcription regulatory region sequence-specific DNA binding"
},
"description": [
"Binding to a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II."
],
"comment": [
"To minimize ambiguity in the use of the word \"promoter\" in GO, we have chosen the phrase \"transcription regulatory region\" to refer to all of the regulatory regions. Regulatory regions in the DNA which control initiation may include the \"core promoter\" where the basal transcription machinery binds, the \"core promoter proximal region\" where regulatory factors other than the basal machinery bind. There are also additional regulatory regions, in both the DNA and the RNA transcript, which regulate elongation or termination of transcription."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0000976",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0000976",
"label": "transcription cis-regulatory region binding"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_related_synonym",
"label": "RNA polymerase II regulatory region DNA binding",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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